Financial Update: Interactive Telesis Reports Results. eBioinformatics & Empatheon Merge.

December 15, 2000

SHORT TAKES

INTERACTIVE TELESIS REPORTS RESULTS

New York, N.Y. — Interactive Telesis Inc., an innovator of speech-enabled hosting services, announced consolidated financial results for the first quarter which ended Oct. 31, 2000. Unaudited consolidated revenues for the first fiscal quarter were $790, 208 with a consolidated net loss of $1,418,478. This represents a revenue decrease of 34% from the first quarter of fiscal 2000. As reported previously, the decrease was primarily due to the loss of AT&T, a Record and Replay customer. The first quarter consolidated net loss of $1,418,478 reflects the inclusion of the company’s share of losses of $151,205 incurred during the period by Paragon Voice Systems (Paragon) along with the amortization of $31,280 in goodwill associated with the acquisition of Paragon.

“The company’s first quarter results reflect our on-going investment in expanding our voice network,” said Donald E. Cameron, chief executive officer of Interactive Telesis. “This expansion will position the company as a major player in the emerging speech recognition market – a market that industry analysts predict to be a multi-billion dollar market by 2005.” “With the recent capital infusion from Hambrecht and Quist Guaranty Finance, the company plans to continue this infrastructure build-out,” added William R. Adams, chief financial officer of Interactive Telesis. “Voice hosting requires a significant capital investment up front, but the market opportunity and recurring revenue potential present a tremendous upside.” The Kelsey Group forecasts that the voice medium will create a $12 billion voice “e-cosystem” by 2005. Interactive Telesis is emerging as a key player in the growing voice applications segment of this market. Recently, Interactive Telesis expanded its voice hosting infrastructure into Exodus Communications, the largest Internet data center company. The expansion will facilitate the rapid deployment and immediate scalability of speech applications for Interactive Telesis customers. For additional information, visit http://www.interactivetelesis.com .

eBioinformatics and Empatheon Merge

Sunnyvale, CALIF. — Entigen Corporation announced its formation from the merger of eBioinformatics, Inc., and Empatheon, Inc. eBioinformatics, formerly of Pleasanton, California is a life-science Application Service Provider (ASP). Empatheon, of Sunnyvale, California, is a life science data integration company providing solutions for secure, real-time access to public and private global genomics and proteomics information. The merger will enrich the life science community’s popular BioNavigator application service, begun by eBioinformatics in 1999, by enabling real-time integration of up-to-date biological data from disparate sources. eBioinformatics has relocated from their former headquarters in Pleasanton, California, to combine operations with Empatheon in the space formerly occupied by Empatheon alone, in Sunnyvale, California. The shareholders from both companies have approved the merger.

Entigen will integrate Empatheon’s data management and access technology with eBioinformatics’ domain knowledge of bioinformatics and its Internet-based BioNavigator application service to improve the way life science researchers access and use data. The current data warehouse approach to managing biological data no longer serves the needs of life scientists, who need readily addressable, real-time access to all types of biological information. Under the data warehouse paradigm, scientists must access many different data sources, using separate, data-specific software, in an attempt to query all available data relative to their investigations. Presently, to investigate a single topic, a scientist might be required to separately examine several different databases each of genetic, proteomic, bibliographic, and patent information, often using separate software applications to address each database. The data warehouse approach also prevents real-time access to constantly expanding biological databases, since database managers must collect, reformat, and assimilate the continuous worldwide production of new biological data, and republish their databases at intervals.

New technology developed by Empatheon – Advanced Dynamic Access, Analysis and Personalization Technology (ADAAPT) – solves the problems researchers face when attempting to analyze isolated, incompatible life science data sources. ADAAPT uses Java-based applications to take the place of a data warehouse and mediates real-time access between scientists and the multiple sources of data they need to access. ADAAPT enables access to all current data resources relevant to scientific investigations from a single, browser-based graphical user interface. Java applications also upgrade the user interface automatically, to inform users that new life science databases have entered the application service.

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