TACC, MD Anderson, and UT Austin: Uniting for Major Strides in Cancer Research

December 12, 2023

Dec. 12, 2023 — The Oden Institute for Computational Engineering and SciencesThe University of Texas MD Anderson Cancer Center, and the Texas Advanced Computing Center (TACC) announced funding for five cancer research projects as part of the program in Oncological Data and Computational Science.

This collaborative effort, launched in 2020, is designed to support research that can accelerate approaches to address unmet needs for patients with cancer. The program aligns the computational research and mathematical modeling strengths of TACC and the Oden Institute with MD Anderson’s oncology and data science expertise, including the institution’s recently launched Institute for Data Science in Oncology.

This year marks the fourth round of seed funding. The program has funded three new projects which bring together collaborators from research units across MD Anderson and UT Austin, and has continued support for two previous seed projects over this funding cycle.

Each new seed project receives grant funding of $50,000, split between both MD Anderson and UT Austin. Computational elements of each project can also tap into TACC’s high performance computing platforms. Ernesto Lima, a research associate at the Oden Institute’s Center for Computational Oncology, will support researchers with the implementation of these project elements.

Tom Yankeelov, director of the Oden Institute’s Center for Computational Oncology and John Hazle, chair of Imaging Physics at MD Anderson, co-lead the collaborative effort.

“I am enthusiastic about this year’s cohort of funded projects, which represent a combination of translational and clinical research,” Yankeelov said. “We are hopeful this innovative work will yield clinically actionable predictions that can improve outcomes for patients with a variety of cancers.”

The funded research projects include:

  • Imaging-based forecasting of prostate cancer histopathology and progression during active surveillance: This project is spearheaded by Thomas J.R. Hughes, lead of the Computational Mechanics Group, and core faculty member at the Oden Institute, and Aradhana Venkatesan, professor of Abdominal Imaging at MD Anderson. Their work seeks to minimize under- and over-treatment of prostate cancer using mathematical modelling of patient-specific MRI data that analyzes tissues as cancers grow.
  • Developing a pipeline to automate longitudinal mammography analysis in a large prospective breast cancer screening cohort: A research team led by Olena Weaver, associate professor of Breast Imaging at MD Anderson, and Edward Castillo, associate professor of Biomedical Engineering and affiliated faculty member at the Oden Institute, seeks to develop a comprehensive, computerized system for rapid mammography analysis. The team hopes to improve the accuracy and specificity with which breast cancers can be diagnosed by using longitudinal mammography and clinical reports analyzed by deep learning and natural language processing.
  • Safe, accurate assessment of treatment response via dynamic contrast enhanced multispectral optoacoustic tomography imaging of tumor perfusion: Tumor perfusion, which refers to the passage of blood and fluid through a tumor, can be of critically important in determining the efficacy of specific cancer therapies. Mark Pagel, professor of Cancer Systems Imaging at MD Anderson, and Umberto Villa, research scientist at the Oden Institute’s Center for Predictive Engineering and Computational Sciences and OPTIMUS Center, respectively, aim to develop robust optical imaging techniques to measure blood flow. These will serve as potential tools to monitor treatment responses across a wide range of cancers. By blending multispectral and optoacoustic imaging methods, this project aims to reduce imaging risk while enhancing the predictive accuracy of treatment analysis.

Previously funded seed project receiving continued support:

  • Single-cell network-based transfer learning model for designing precision medicine in colorectal cancer: By using pre-trained machine learning models, Stephen Yi, who is director of the Bioinformatics and the Developmental Therapeutics Lab at Dell Medical School and Oden Institute affiliated faculty member, and Scott Kopetz, professor of Gastrointestinal Medical Oncology at MD Anderson, are working to design personalized medicine solutions for colorectal cancers. This is a previously funded seed project receiving continued support in this funding cycle.
  • Rapid, motion-robust MRI for fast and affordable prostate cancer screening and surveillance: In an effort to make prostate MRIs faster and more accurate, reducing the rate of unnecessary biopsies, Ken-Pin Hwang, assistant professor of Imaging Physics at MD Anderson, and Jon Tamir, assistant professor with UT Austin’s Department of Electrical and Computer Engineering and Oden Institute affiliated faculty, will blend mathematical modeling and massively parallel distributed computing. This is a previously funded seed project receiving continued support in this funding cycle.

“The collaboration between MD Anderson and UT Austin faculty demonstrates the power of team science in addressing significant cancer challenges,” Hazle said. “We’ve seen exciting results from prior funded projects, and we are optimistic that these current projects will lead to highly impactful, externally funded awards.”


Source: Aira Balasubramanian and Joanne Foote, Oden Institute

Subscribe to HPCwire's Weekly Update!

Be the most informed person in the room! Stay ahead of the tech trends with industry updates delivered to you every week!

A Big Memory Nvidia GH200 Next to Your Desk: Closer Than You Think

February 22, 2024

Students of the microprocessor may recall that the original 8086/8088 processors did not have floating point units. The motherboard often had an extra socket for an optional 8087 math coprocessor. The math coprocessor ma Read more…

IonQ Reports Advance on Path to Networked Quantum Computing

February 22, 2024

IonQ reported reaching a milestone in its efforts to use entangled photon-ion connectivity to scale its quantum computers. IonQ’s quantum computers are based on trapped ions which feature long coherence times and qubit Read more…

Apple Rolls out Post Quantum Security for iOS

February 21, 2024

Think implementing so-called Post Quantum Cryptography (PQC) isn't important because quantum computers able to decrypt current RSA codes don’t yet exist? Not Apple. Today the consumer electronics giant started rolling Read more…

GenAI Having Major Impact on Data Culture, Survey Says

February 21, 2024

While 2023 was the year of GenAI, the adoption rates for GenAI did not match expectations. Most organizations are continuing to invest in GenAI but are yet to derive any substantial value from it. However, the GenAI hyp Read more…

QED-C Issues New Quantum Benchmarking Paper

February 20, 2024

The Quantum Economic Development Consortium last week released a new paper on benchmarking – Quantum Algorithm Exploration using Application-Oriented Performance Benchmarks – that builds on earlier work and is an eff Read more…

AWS Solution Channel

Shutterstock 2283618597

Deep-dive into Ansys Fluent performance on Ansys Gateway powered by AWS

Today, we’re going to deep-dive into the performance and associated cost of running computational fluid dynamics (CFD) simulations on AWS using Ansys Fluent through the Ansys Gateway powered by AWS (or just “Ansys Gateway” for the rest of this post). Read more…

Atom Computing Reports Advance in Scaling Up Neutral Atom Qubit Arrays

February 15, 2024

The scale-up challenge facing quantum computing (QC) is daunting and varied. It’s commonly held that 1 million qubits (or more) will be needed to deliver practical fault tolerant QC. It’s also a varied challenge beca Read more…

A Big Memory Nvidia GH200 Next to Your Desk: Closer Than You Think

February 22, 2024

Students of the microprocessor may recall that the original 8086/8088 processors did not have floating point units. The motherboard often had an extra socket fo Read more…

Apple Rolls out Post Quantum Security for iOS

February 21, 2024

Think implementing so-called Post Quantum Cryptography (PQC) isn't important because quantum computers able to decrypt current RSA codes don’t yet exist? Not Read more…

QED-C Issues New Quantum Benchmarking Paper

February 20, 2024

The Quantum Economic Development Consortium last week released a new paper on benchmarking – Quantum Algorithm Exploration using Application-Oriented Performa Read more…

The Pulse of HPC: Tracking 4.5 Million Heartbeats of 3D Coronary Flow

February 15, 2024

Working in Duke University's Randles Lab, Cyrus Tanade, a National Science Foundation graduate student fellow and Ph.D. candidate in biomedical engineering, is Read more…

It Doesn’t Get Much SWEETER: The Winter HPC Computing Festival in Corpus Christi

February 14, 2024

(Main Photo by Visit Corpus Christi CrowdRiff) Texas A&M University's High-Performance Research Computing (HPRC) team hosted the "SWEETER Winter Comput Read more…

Q-Roundup: Diraq’s War Chest, DARPA’s Bet on Topological Qubits, Citi/Classiq Explore Optimization, WEF’s Quantum Blueprint

February 13, 2024

Yesterday, Australian start-up Diraq added $15 million to its war chest (now $120 million) to build a fault tolerant computer based on quantum dots. Last week D Read more…

2024 Winter Classic: Razor Thin Margins in HPL/HPCG

February 12, 2024

The first task for the 11 teams in the 2024 Winter Classic student cluster competition was to run and optimize the LINPACK and HPCG benchmarks. As usual, the Read more…

2024 Winter Classic: We’re Back!

February 9, 2024

The fourth edition of the Winter Classic Invitational Student Cluster Competition is up and running. This year, we have 11 teams of eager students representin Read more…

CORNELL I-WAY DEMONSTRATION PITS PARASITE AGAINST VICTIM

October 6, 1995

Ithaca, NY --Visitors to this year's Supercomputing '95 (SC'95) conference will witness a life-and-death struggle between parasite and victim, using virtual Read more…

SGI POWERS VIRTUAL OPERATING ROOM USED IN SURGEON TRAINING

October 6, 1995

Surgery simulations to date have largely been created through the development of dedicated applications requiring considerable programming and computer graphi Read more…

U.S. Will Relax Export Restrictions on Supercomputers

October 6, 1995

New York, NY -- U.S. President Bill Clinton has announced that he will definitely relax restrictions on exports of high-performance computers, giving a boost Read more…

Dutch HPC Center Will Have 20 GFlop, 76-Node SP2 Online by 1996

October 6, 1995

Amsterdam, the Netherlands -- SARA, (Stichting Academisch Rekencentrum Amsterdam), Academic Computing Services of Amsterdam recently announced that it has pur Read more…

Cray Delivers J916 Compact Supercomputer to Solvay Chemical

October 6, 1995

Eagan, Minn. -- Cray Research Inc. has delivered a Cray J916 low-cost compact supercomputer and Cray's UniChem client/server computational chemistry software Read more…

NEC Laboratory Reviews First Year of Cooperative Projects

October 6, 1995

Sankt Augustin, Germany -- NEC C&C (Computers and Communication) Research Laboratory at the GMD Technopark has wrapped up its first year of operation. Read more…

Sun and Sybase Say SQL Server 11 Benchmarks at 4544.60 tpmC

October 6, 1995

Mountain View, Calif. -- Sun Microsystems, Inc. and Sybase, Inc. recently announced the first benchmark results for SQL Server 11. The result represents a n Read more…

New Study Says Parallel Processing Market Will Reach $14B in 1999

October 6, 1995

Mountain View, Calif. -- A study by the Palo Alto Management Group (PAMG) indicates the market for parallel processing systems will increase at more than 4 Read more…

Leading Solution Providers

Contributors

CORNELL I-WAY DEMONSTRATION PITS PARASITE AGAINST VICTIM

October 6, 1995

Ithaca, NY --Visitors to this year's Supercomputing '95 (SC'95) conference will witness a life-and-death struggle between parasite and victim, using virtual Read more…

SGI POWERS VIRTUAL OPERATING ROOM USED IN SURGEON TRAINING

October 6, 1995

Surgery simulations to date have largely been created through the development of dedicated applications requiring considerable programming and computer graphi Read more…

U.S. Will Relax Export Restrictions on Supercomputers

October 6, 1995

New York, NY -- U.S. President Bill Clinton has announced that he will definitely relax restrictions on exports of high-performance computers, giving a boost Read more…

Dutch HPC Center Will Have 20 GFlop, 76-Node SP2 Online by 1996

October 6, 1995

Amsterdam, the Netherlands -- SARA, (Stichting Academisch Rekencentrum Amsterdam), Academic Computing Services of Amsterdam recently announced that it has pur Read more…

Cray Delivers J916 Compact Supercomputer to Solvay Chemical

October 6, 1995

Eagan, Minn. -- Cray Research Inc. has delivered a Cray J916 low-cost compact supercomputer and Cray's UniChem client/server computational chemistry software Read more…

NEC Laboratory Reviews First Year of Cooperative Projects

October 6, 1995

Sankt Augustin, Germany -- NEC C&C (Computers and Communication) Research Laboratory at the GMD Technopark has wrapped up its first year of operation. Read more…

Sun and Sybase Say SQL Server 11 Benchmarks at 4544.60 tpmC

October 6, 1995

Mountain View, Calif. -- Sun Microsystems, Inc. and Sybase, Inc. recently announced the first benchmark results for SQL Server 11. The result represents a n Read more…

New Study Says Parallel Processing Market Will Reach $14B in 1999

October 6, 1995

Mountain View, Calif. -- A study by the Palo Alto Management Group (PAMG) indicates the market for parallel processing systems will increase at more than 4 Read more…

  • arrow
  • Click Here for More Headlines
  • arrow
HPCwire