The Living Heart Project Wins Three Prestigious Awards for HPC Simulation

By Bill Mannel, VP & GM, HPC Segment Solutions and Apollo Servers, Data Center Infrastructure Group, Hewlett Packard Enterprise

December 20, 2017

Imagine creating a treatment plan for a patient on the other side of the world, or testing a drug without ever putting subjects at risk. 3D modeling and simulation tools have opened the door to a new age of healthcare. Operations like the Living Heart Project are uniting industry-leading researchers, doctors, educators, and technology manufacturers to reach a higher standard for personalized medicine. Leveraging advanced modeling and simulation capabilities, the Living Heart Project has developed highly accurate, validated models of the human heart which can be personalized by patients’ unique traits and conditions. The Living Heart Project is a growing ecosystem that is fueling the collaborative development of commercially available heart models and exploring novel digital therapies.

Today, life sciences organizations are harnessing modeling and simulation tools backed by the latest high performance computing (HPC) innovations to virtually analyze their patients’ health records, plan therapies, and practice surgical procedures. These realistic models will serve as a common technology base for education and training, medical device design, testing, clinical diagnosis, and regulatory science—working to both enhance and accelerate patient care.

Next-generation technology for modern healthcare

The latest Living Heart Project, a study on drug-induced heart arrhythmias, resulted from the cooperation between Stanford University, Dassault Systèmes, UberCloud, Hewlett Packard Enterprise (HPE), and Advania. The collaboration received three prestigious HPC awards during SC’17.

The Living Matter Laboratory of Stanford University is now using HPC simulations to study the potentially lethal side effects of drugs—such as heart arrhythmias, which occur when electrical activity in the heart turns chaotic. Utilizing a multi-scale 3D model, researchers can monitor blood circulation and predict the risk of drug-induced arrhythmias, based on a variety of cell types within the tissue. The model allows researchers to assess the response of new drug compounds (like Quinidine – below) quickly and cost-effectively before it is released on the market.

Source: UberCloud 2017

For this study, the Stanford Living Heart Project—in conjunction with SIMULIA, UberCloud, HPE, and Advania—introduced a containerized version of the Living Heart Model, developed by UberCloud and based on HPE Apollo systems, that enables drug developers to virtually test and ultimately prevent harmful side effects. Researchers can now test 250,000,000 internal variables which are updated and stored within each step of the simulation. To date, the Stanford University team has run 42 simulations (each taking 40 hours to complete on a 5-node system) to determine whether a drug may cause arrhythmias. Thanks to HPE Apollo systems, simulations can run seamlessly on-premises, off-premises, and in the cloud with no compromise on performance, costs, or service-level agreement (SLA).

The digital healthcare revolution

HPC is driving major breakthroughs in life sciences and becoming foundational to success. Today, HPE is harnessing the extreme scalability of the cloud to maximize agility and scalability both on and off-premises. In order to support groundbreaking efforts like the Living Heart Project, HPE is building a network of worldwide and regional HPC Cloud service providers to deliver capabilities that are changing lives.

Utilizing a Hybrid HPC approach, the Living Heart Project and its partners designed a simulation software tool to ensure optimal performance, usability, and security. With the creation of this innovative heart model, researchers will have the opportunity to increase the number of successful drugs on the market and rapidly improve patient care, while decreasing the time and cost of production.

The Living Heart Project was presented three prestigious awards for their efforts in HPC simulation, including the Hyperion Award for Innovation Excellence, the HPCwire Editors’ Choice Award for Best Use of HPC in the Cloud, as well as being award best paper at the Intel Developer Conference. According to Wolfgang Gentzsch of UberCloud, the entire Living Heart Project team, led by researchers from the Living Matter Laboratory at Stanford University is “proud and humbled” by these awards as well as “deeply grateful for all the support from HPE and Intel (the sponsors), Dassault Systèmes SIMULIA (for Abaqus 2017), Advania, and the UberCloud tech team for containerizing Abaqus and integrating all software and hardware components into one seamless solution stack.”

To learn more about HPE’s vision for Hybrid HPC, click here to read our dedicated business whitepaper. I also encourage you to follow me on Twitter at @Bill_Mannel to explore how the Living Heart Project is revolutionizing patient care. And check out @HPE_HPC for up-to-the-minute news on HPC solutions for life sciences and other HPE innovations.

Return to Solution Channel Homepage

HPE Resources

Follow @HPE_HPC

HPE on Facebook

Subscribe to HPCwire's Weekly Update!

Be the most informed person in the room! Stay ahead of the tech trends with industy updates delivered to you every week!

Neural Network ‘Synapse’ Technology Showcased at IEEE Meeting

December 12, 2018

There’s nice snapshot of advancing work to develop improved neural network “synapse” technologies posted yesterday on IEEE Spectrum. Lower power, ease of use, manufacturability, and performance are all key paramete Read more…

By John Russell

Is Amazon’s Plunge into Server Chips a Watershed Moment?

December 11, 2018

For several years now the big cloud providers – Amazon, Microsoft Azure, Google, et al – have been transforming from technology consumers into technology creators in hardware and software. The most recent example bei Read more…

By John Russell

Mellanox Uses Univa to Extend Silicon Design HPC Operation to Azure

December 11, 2018

Call it a corollary to Murphy’s Law: When a system is most in demand, when end users are most dependent on the system performing as required, when it’s crunch time – that’s when the system is most likely to blow up. Or make you wait in line to use it. Read more…

By Doug Black

HPE Extreme Performance Solutions

AI Can Be Scary. But Choosing the Wrong Partners Can Be Mortifying!

As you continue to dive deeper into AI, you will discover it is more than just deep learning. AI is an extremely complex set of machine learning, deep learning, reinforcement, and analytics algorithms with varying compute, storage, memory, and communications needs. Read more…

IBM Accelerated Insights

Blurring the Lines Between HPC and AI @ SC18

The dominant topic at SC18 was the convergence of HPC and Artificial Intelligence (AI) with some of the biggest research and enterprise HPC users providing perspectives on how HPC and AI are moving closer together. Read more…

Clemson’s Cautionary Cryptomining Tale

December 11, 2018

In some ways, the bigger the computer, the more vulnerable it is to cryptomining as Clemson University discovered after cryptominers dug into its Palmetto supercomputer. When a number of nodes on Clemson University’s P Read more…

By Staff

Topology Can Help Us Find Patterns in Weather

December 6, 2018

Topology--–the study of shapes-- seems to be all the rage. You could even say that data has shape, and shape matters. Shapes are comfortable and familiar conc Read more…

By James Reinders

Zettascale by 2035? China Thinks So

December 6, 2018

Exascale machines (of at least a 1 exaflops peak) are anticipated to arrive by around 2020, a few years behind original predictions; and given extreme-scale performance challenges are not getting any easier, it makes sense that researchers are already looking ahead to the next big 1,000x performance goal post: zettascale computing. Read more…

By Tiffany Trader

Robust Quantum Computers Still a Decade Away, Says Nat’l Academies Report

December 5, 2018

The National Academies of Science, Engineering, and Medicine yesterday released a report – Quantum Computing: Progress and Prospects – whose optimism about Read more…

By John Russell

Revisiting the 2008 Exascale Computing Study at SC18

November 29, 2018

A report published a decade ago conveyed the results of a study aimed at determining if it were possible to achieve 1000X the computational power of the the Read more…

By Scott Gibson

AWS Debuts Lustre as a Service, Accelerates Data Transfer

November 28, 2018

From the Amazon re:Invent main stage in Las Vegas today, Amazon Web Services CEO Andy Jassy introduced Amazon FSx for Lustre, citing a growing body of applicati Read more…

By Tiffany Trader

AWS Launches First Arm Cloud Instances

November 28, 2018

AWS, a macrocosm of the emerging high-performance technology landscape, wants to be everywhere you want to be and offer everything you want to use (or at least Read more…

By Doug Black

Move Over Lustre & Spectrum Scale – Here Comes BeeGFS?

November 26, 2018

Is BeeGFS – the parallel file system with European roots – on a path to compete with Lustre and Spectrum Scale worldwide in HPC environments? Frank Herold Read more…

By John Russell

DOE Under Secretary for Science Paul Dabbar Interviewed at SC18

November 21, 2018

During the 30th annual SC conference in Dallas last week, SC18 hosted U.S. Department of Energy Under Secretary for Science Paul M. Dabbar. In attendance Nov. 13-14, Dabbar delivered remarks at the Top500 panel, met with a number of industry stakeholders and toured the show floor. He also met with HPCwire for an interview, where we discussed the role of the DOE in advancing leadership computing. Read more…

By Tiffany Trader

Quantum Computing Will Never Work

November 27, 2018

Amid the gush of money and enthusiastic predictions being thrown at quantum computing comes a proposed cold shower in the form of an essay by physicist Mikhail Read more…

By John Russell

Cray Unveils Shasta, Lands NERSC-9 Contract

October 30, 2018

Cray revealed today the details of its next-gen supercomputing architecture, Shasta, selected to be the next flagship system at NERSC. We've known of the code-name "Shasta" since the Argonne slice of the CORAL project was announced in 2015 and although the details of that plan have changed considerably, Cray didn't slow down its timeline for Shasta. Read more…

By Tiffany Trader

IBM at Hot Chips: What’s Next for Power

August 23, 2018

With processor, memory and networking technologies all racing to fill in for an ailing Moore’s law, the era of the heterogeneous datacenter is well underway, Read more…

By Tiffany Trader

House Passes $1.275B National Quantum Initiative

September 17, 2018

Last Thursday the U.S. House of Representatives passed the National Quantum Initiative Act (NQIA) intended to accelerate quantum computing research and developm Read more…

By John Russell

Summit Supercomputer is Already Making its Mark on Science

September 20, 2018

Summit, now the fastest supercomputer in the world, is quickly making its mark in science – five of the six finalists just announced for the prestigious 2018 Read more…

By John Russell

CERN Project Sees Orders-of-Magnitude Speedup with AI Approach

August 14, 2018

An award-winning effort at CERN has demonstrated potential to significantly change how the physics based modeling and simulation communities view machine learni Read more…

By Rob Farber

AMD Sets Up for Epyc Epoch

November 16, 2018

It’s been a good two weeks, AMD’s Gary Silcott and Andy Parma told me on the last day of SC18 in Dallas at the restaurant where we met to discuss their show news and recent successes. Heck, it’s been a good year. Read more…

By Tiffany Trader

US Leads Supercomputing with #1, #2 Systems & Petascale Arm

November 12, 2018

The 31st Supercomputing Conference (SC) - commemorating 30 years since the first Supercomputing in 1988 - kicked off in Dallas yesterday, taking over the Kay Ba Read more…

By Tiffany Trader

Leading Solution Providers

SC 18 Virtual Booth Video Tour

Advania @ SC18 AMD @ SC18
ASRock Rack @ SC18
DDN Storage @ SC18
HPE @ SC18
IBM @ SC18
Lenovo @ SC18 Mellanox Technologies @ SC18
NVIDIA @ SC18
One Stop Systems @ SC18
Oracle @ SC18 Panasas @ SC18
Supermicro @ SC18 SUSE @ SC18 TYAN @ SC18
Verne Global @ SC18

TACC’s ‘Frontera’ Supercomputer Expands Horizon for Extreme-Scale Science

August 29, 2018

The National Science Foundation and the Texas Advanced Computing Center announced today that a new system, called Frontera, will overtake Stampede 2 as the fast Read more…

By Tiffany Trader

HPE No. 1, IBM Surges, in ‘Bucking Bronco’ High Performance Server Market

September 27, 2018

Riding healthy U.S. and global economies, strong demand for AI-capable hardware and other tailwind trends, the high performance computing server market jumped 28 percent in the second quarter 2018 to $3.7 billion, up from $2.9 billion for the same period last year, according to industry analyst firm Hyperion Research. Read more…

By Doug Black

Nvidia’s Jensen Huang Delivers Vision for the New HPC

November 14, 2018

For nearly two hours on Monday at SC18, Jensen Huang, CEO of Nvidia, presented his expansive view of the future of HPC (and computing in general) as only he can do. Animated. Backstopped by a stream of data charts, product photos, and even a beautiful image of supernovae... Read more…

By John Russell

Germany Celebrates Launch of Two Fastest Supercomputers

September 26, 2018

The new high-performance computer SuperMUC-NG at the Leibniz Supercomputing Center (LRZ) in Garching is the fastest computer in Germany and one of the fastest i Read more…

By Tiffany Trader

Houston to Field Massive, ‘Geophysically Configured’ Cloud Supercomputer

October 11, 2018

Based on some news stories out today, one might get the impression that the next system to crack number one on the Top500 would be an industrial oil and gas mon Read more…

By Tiffany Trader

Intel Confirms 48-Core Cascade Lake-AP for 2019

November 4, 2018

As part of the run-up to SC18, taking place in Dallas next week (Nov. 11-16), Intel is doling out info on its next-gen Cascade Lake family of Xeon processors, specifically the “Advanced Processor” version (Cascade Lake-AP), architected for high-performance computing, artificial intelligence and infrastructure-as-a-service workloads. Read more…

By Tiffany Trader

Google Releases Machine Learning “What-If” Analysis Tool

September 12, 2018

Training machine learning models has long been time-consuming process. Yesterday, Google released a “What-If Tool” for probing how data point changes affect a model’s prediction. The new tool is being launched as a new feature of the open source TensorBoard web application... Read more…

By John Russell

The Convergence of Big Data and Extreme-Scale HPC

August 31, 2018

As we are heading towards extreme-scale HPC coupled with data intensive analytics like machine learning, the necessary integration of big data and HPC is a curr Read more…

By Rob Farber

  • arrow
  • Click Here for More Headlines
  • arrow
Do NOT follow this link or you will be banned from the site!
Share This